Table 1.
Baseline characteristics and outcome in cervical arterial dissection patients with acute stroke using nonvitamin K oral anticoagulants or vitamin K antagonists
| NOAC (n = 6; 8.8%) | VKA (n = 62; 91%) | All (n = 68) | |
|---|---|---|---|
| Age, median (IQR) | 44 (38–46) | 46 (39–53) | 45 (39–53) |
| Male gender | 4 (67) | 39 (63) | 43 (63) |
| NIHSS at baseline | 4 (2–5) | 2 (1–7) | 2 (1–6) |
| Vertebral artery dissection | 2 (33) | 38 (61) | 40 (59) |
| Occlusion | 1 (33) | 15 (40) | 16 (39) |
| Stenosis | 2 (67) | 23 (60) | 25 (61) |
| Internal carotid artery dissection | 4 (67) | 27 (44) | 31 (46) |
| Occlusion | 1 (33) | 14 (52) | 15 (50) |
| Stenosis | 2 (67) | 13 (48) | 15 (50) |
| Symptom onset to hospital | 0.5 (0–4.0) | 0.5 (0–1.3) | 0.5 (0–1.8) |
| Prior infection | 3 (50) | 7 (11) | 10 (15) |
| Prior trauma | 0 | 16 (26) | 16 (24) |
| Recanalization | 5 (83) | 34 (55) | 39 (57) |
| Modified Rankin Scale ≤ 1 | 6 (100) | 48 (77) | 54 (79) |
| Intracerebral hemorrhage | 0 | 1 (1.6) | 1 (1.5) |
| Death | 0 | 1 (1.6) | 1 (1.5) |
Values are median (interquartile range) and n (%). NOAC, nonvitamin K oral anticoagulants; VKA, vitamin K antagonists; NIHSS, National Institutes of Health Stroke Scale. Data on recent infection within 1 week and trauma, physical impact on the head or neck within 1 month were obtained from the patient records.