Table 2.
MRI characteristics in a series of patients with delayed posthypoxic leukoencephalopathy
| No. | Time to MRI1 (days) | Morphology of signal abnormality | Symmetry | T2-FLAIR/ADC mismatch | Spared structures | Mass effect or gyral edema | Contrast enhancement | Hemorrhage |
|---|---|---|---|---|---|---|---|---|
| 1 | 40 | Patchy | Yes | T2-FLAIR more extensive than ADC | U-fibers, brainstem, basal ganglia, thalami, cerebellum | No | No | No |
| 2 | 50 | Homogeneous | Yes | T2-FLAIR more extensive than ADC | Same as above | No | No | No |
| 3 | 54 | Patchy | Yes | Matched T2-FLAIR/ADC | Same as above | No | No | No |
| 4 | 30 | Homogeneous | Yes | T2-FLAIR more extensive than ADC | Same as above | No | No | No |
| 5 | 20 | Patchy | Yes | Matched T2-FLAIR/ADC ADC | Same as above | No | No | No |
Time to MRI abnormality since the original hypoxic event (during relapse).
MRI, magnetic resonance imaging; ADC, apparent diffusion coefficient; FLAIR, fluid-attenuated inversion recovery.