Table 2.

Bivariate and multivariate analysis of factors determining 5 year DSS and OS in patients with bladder cancer over the age of 70 years

	DSS		OS
	Bivariate (95% CI)	Multivariate (95% CI)	Bivariate (95% CI)	Multivariate (95% CI)
Sex (female)	1.51 (1.35–1.68)	1.27 (1.14–1.43)	1.19 (1.09–1.29)	1.03 (0.95–1.12)
Age	1.06 (1.05–1.07)	1.07 (1.06–1.08)	1.07 (1.06–1.08)	1.07 (1.07–1.08)
Charlson comorbidity
0	1	1	1	1
1	1.44 (1.24–1.68)	1.27 (1.09–1.48)	1.56 (1.40–1.74)	1.4 (1.25–1.56)
≥2	2.15 (1.91–2.42)	1.89 (1.68–2.14)	2.35 (2.15–2.57)	2.07 (1.89–2.27)
Stage
Localized	1	1	1	1
Regional	2.37 (2.06–2.74)	2.36 (2.04–2.74)	1.66 (1.48–1.85)	1.68 (1.50–1.88)
Distant	8.50 (7.24–9.97)	7.65 (6.48–9.04)	5.31 (4.63–6.10)	4.84 (4.20–5.58)
Unknown	1.35 (1.17–1.56)	1.29 (1.12–1.49)	1.29 (1.17–1.42)	1.22 (1.10–1.34)
Cystectomy
Yes	1	1	1	1
No	1.06 (0.90–1.24)	0.91 (0.76–1.08)	1.38 (1.21–1.58)	1.11 (0.97–1.29)
Intravesical therapy
Yes	1	1	1	1
No	2.45 (1.96–3.07)	1.86 (1.48–2.34)	2.02 (1.74–2.35)	1.77 (1.52–2.07)
Intravenous therapy
Yes	1	1	1	1
No	0.76 (0.62–0.94)	0.83 (0.66–1.03)	0.86 (0.72–1.01)	0.77 (0.65–0.92)
Hospital of primary treatment
Public	1	1	1	1
Private	0.63 (0.57–0.70)	0.67 (0.60–0.75)	0.68 (0.63–0.73)	0.70 (0.64–0.76)
Socioeconomic status SEIFA
Least disadvantaged (Quintile 1)	1	1	1	1
Quintile 2	0.85 (0.71–1.02)	0.88 (0.73–1.07)	0.94 (0.82–1.08)	0.97 (0.84–1.11)
Quintile 3	1.07 (0.91–1.26)	1.17 (0.98–1.39)	1.09 (0.97–1.23)	1.17 (1.03–1.33)
Quintile 4	1.01 (0.86–1.19)	1.15 (0.97–1.37)	1.03 (0.91–1.16)	1.12 (0.98–1.27)
Most disadvantaged (Quintile 5)	0.98 (0.82–1.16)	1.03 (0.86–1.25)	1.11 (0.97–1.26)	1.16 (1.01–1.34)
Remoteness of residence (ARIA)
Major cities	1	1	1	1
Inner regional	0.99 (0.87–1.12)	0.98 (0.85–1.12)	0.99 (0.90–1.09)	0.95 (0.86–1.06)
Outer regional/remote	1.07 (0.86–1.32)	1.03 (0.82–1.29)	1.05 (0.90–1.24)	0.97 (0.82–1.15)

DSS, disease specific survival; OS, overall survival; ARIA, Accessibility/Remoteness Index of Australia.