Table 7.
Locoregional-free rate | Distant metastasis-free rate | ||||||
---|---|---|---|---|---|---|---|
Univariate analysis | |||||||
Factor | Level (n) | HR1 | 95% CI | P-value | HR1 | 95% CI | P-value |
Age | <50 (36) | 1 | 0.4715–5.200 | 0.4604 | 1 | 0.330–3.278 | 0.9462 |
≥50 (50) | 1.566 | 1.040 | |||||
Gender | Male (66) | 1 | 0, infty | 0.0303 | 1 | 0.116–2.417 | 0.4037 |
Female (21) | Near 0 | 0.529 | |||||
TNM primary | 1 or 2 (52) | 1 | 0.956–10.548 | 0.0464 | 1 | 0.492–4.735 | 0.4602 |
3 or 4 (35) | 3.175 | 1.527 | |||||
TNM LN | 0 or 1 (33) | 1 | 0.761–15.925 | 0.0866 | 1 | 0, infty | 0.0032 |
2 or 3 (54) | 3.482 | Infty | |||||
Stage | IIB or III (58) | 1 | 0.318–3.518 | 0.9262 | 1 | 1.390–15.379 | 0.0060 |
IV (29) | 1.058 | 4.624 | |||||
WHO pathology | I (18) | 1 | 0.099–0.986 | 0.0359 | 1 | 0, infty | 0.0850 |
II or III(69) | 0.312 | infty | |||||
PS | 0 (73) | 1 | 0.476–6.503 | 0.3902 | 1 | 0.252–5.250 | 0.8572 |
1 or 2 (14) | 1.760 | 1.149 | |||||
RT dose primary | <70 (5) | 1 | 0.064–1.340 | 0.0924 | 1 | 0, infty | 0.4078 |
≥70 (81) | 0.293 | infty | |||||
RT dose LN | <70 (21) | 1 | 0.254–3.471 | 0.9255 | 1 | 0.356–7.407 | 0.5279 |
≥70 (65) | 0.940 | 1.622 | |||||
Total dose of 5-FU | <12,000 (37) | 1 | 0.135–1.349 | 0.1354 | 1 | 0.143–1.429 | 0.1657 |
≥12,000 (50) | 0.427 | 0.453 | |||||
Total dose of CDDP | <300 (38) | 1 | 0.210–2.024 | 0.4560 | 1 | 0.096–1.060 | 0.0490 |
≥300 (49) | 0.652 | 0.319 | |||||
OTT2 | <87 (38) | 1 | 0.126–1.474 | 0.1673 | 1 | 0.238–2.291 | 0.5986 |
≥87 (47) | 0.431 | 0.739 |
Hazard ratio.
Overall treatment time.