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. 2015 May 20;4(8):1303–1308. doi: 10.1002/cam4.474

Table 3.

The HR of invasive breast cancer associated with different type of HT prescription and different duration of use in 2004–2005

Prescription in DDD Estrogen and progesterone combinations Systemic estrogens Tibolone Vaginal estrogens
Number HR Number HR Number HR Number HR
0 3584 1 4398 1 4390 1 4265 1
1–180 134 1.07 (0.90–1.27 41 0.86 (0.63–1.17) 66 1.32 (1.03–1.68) 290 0.84 (0.74–0.95)
181–365 135 1.24 (1.04–1.47) 52 1.12 (0.85–1.48) 41 1.16 (0.85–1.60) 35 0.93 (0.66–1.30)
>365 744 2.06 (1.90–2.24) 106 1.03 (0.85–1.25) 100 1.23 (1.01–1.51) 7 0.65 (0.31–1.37)

All values are adjusted for age, number of child births, whether or not the women attended the screening program in 2004–2009 and whether or not a nonuser in 2004–2005 started with HT use in 2006–2009.