Table 2.
Baseline and outcome data of lipid profiles of randomized controlled trials (n = 6) on continuous positive airway pressure effects on lipid metabolism in obstructive sleep apnea
| Studies | Baseline, level (mg/dl) (SD) | Effect size (mg/dl) (95 % CI) | ||||||
|---|---|---|---|---|---|---|---|---|
| T-CHO | TG | HDL | LDL | T-CHO | TG | HDL | LDL | |
| Comondore 2009 [23] | 185.62 (NM) | 162.08 (NM) | 44.47 (NM) | 109.82 (NM) | 4.64 (−15.47~24.75) | −46.06 (−154.11~62) | −2.51 (−8.12~3.09) | 5.41 (−14.69~25.91) |
| Coughlin 2007 [25] | NM (NM) | NM (NM) | NM (NM) | NM (NM) | −7.73 (−19.34~3.87) | −8.86 (−38.72~21.01) | −1.16 (−3.87~1.55) | −3.87 (−11.32~3.58) |
| Craig 2012 [26] | 203 (44.47) | 149.24 (84.1) | 50.27 (13.8) | 121.23 (38.46) | −1.93 (−7.73~3.87) | −3.99 (−14.17~6.2) | −0.58 (−1.93~0.77) | 0 (−5.03~5.03) |
| Drager 2007 [24] | 234 (38.25) | 161.5 (56.73) | 49.5 (8.99) | 152.5 (34.08) | −5 (−34.95~24.95) | 19 (−37.42~75.42) | −1 (−8.09~6.09) | −4 (−29.88~21.88) |
| Phillips 2011 [22] | 197.60 (39.83) | 170.05 (86.80) | 45.24 (10.83) | 121.04 (38.28) | −7.35 (−10.44~−4.25) | −19.04 (−27.46~−10.63) | −1.16 (−1.93~−0.39) | NM |
| Robinson 2004 [13] | 218.49 (46.48) | 262.2 (198.92) | NM | NM | −8.12 (−16.29~0.05) | −16.83 (−52.11~18.45) | NM | NM |
The value was expressed as mean
NM not mentioned, SD standard deviation, T-CHO total cholesterol, TG triglyceride, HDL high-density lipoprotein, LDL low-density lipoprotein