Table 4.
Probabilities of biological activity and action mechanisms for compounds 5–7, 11, 12
Pa/% | ||||||
---|---|---|---|---|---|---|
5 | 6 | 7 | 11 | 12 | ||
Pharmacological action | Antieczematic | 36.6 | 40.2 | 55.6 | 68.5 | 89.6 |
Mucomembranous protector | 78.5 | 55.7 | 61.6 | 62.5 | 83.2 | |
Antiulcerative | 55.6 | 53.7 | 29.8 | 65.9 | 75.2 | |
Antiviral | 49.9 | 60.1 | 57.2 | 52.9 | 66.3 | |
Radioprotector | 46.1 | 65.7 | 67.4 | np | 21.4 | |
Mechanism of action | Chloride peroxidase inhibitor | 71.0 | 61.8 | 52.0 | 43.9 | np |
Muramoyltetrapeptide carboxypeptidase inhibitor | 35.0 | 30.4 | 30.9 | 49.8 | 75.5 | |
Membrane permeability inhibitor | 67.1 | 55.2 | 45.5 | 68.9 | 46.6 | |
Cl−-transporting ATPase inhibitor | 67.7 | 59.4 | 54.3 | 43.1 | 36.2 | |
Gastrin inhibitor | 66.6 | 69.3 | 60.7 | 55.9 | 51.5 |
np Not predicted