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. 2015 Aug 5;146(10):1673–1679. doi: 10.1007/s00706-015-1539-z

Table 4.

Probabilities of biological activity and action mechanisms for compounds 57, 11, 12

Pa/%
5 6 7 11 12
Pharmacological action Antieczematic 36.6 40.2 55.6 68.5 89.6
Mucomembranous protector 78.5 55.7 61.6 62.5 83.2
Antiulcerative 55.6 53.7 29.8 65.9 75.2
Antiviral 49.9 60.1 57.2 52.9 66.3
Radioprotector 46.1 65.7 67.4 np 21.4
Mechanism of action Chloride peroxidase inhibitor 71.0 61.8 52.0 43.9 np
Muramoyltetrapeptide carboxypeptidase inhibitor 35.0 30.4 30.9 49.8 75.5
Membrane permeability inhibitor 67.1 55.2 45.5 68.9 46.6
Cl-transporting ATPase inhibitor 67.7 59.4 54.3 43.1 36.2
Gastrin inhibitor 66.6 69.3 60.7 55.9 51.5

np Not predicted