IL-17A and IFN-γ production predict glucocorticoid responsiveness. A, Comparison of IL-17A and IFN-γ production in patients with SS asthma (solid circles) and patients with SR asthma (open squares). B, Combined production of IL-17A and IFN-γ correlated with change in absolute lung function (ΔFEV1) in response to 2 weeks of prednisolone, as assessed by using the Spearman rank correlation statistical test. C, ROC curves for prediction of steroid resistance based on production of IFN-γ, IL-17A, and their combination.