. 2015 Sep 4;13:101. doi: 10.1186/s12958-015-0100-6

Table 4.

Steroid hormone metabolite[μg/mmol urinary creatinine]

	1^st trimester (n = 81)				2^nd trimester (n = 40)				3^rd trimester (n = 40)
			Reference intervals				Reference intervals				Reference intervals
move to a separate row	Mean ± SD	Median	2.5^th percentile [90 % CI]	97.5^th percentile [90 % CI]	Mean ± SD	Median	2.5^th percentile [90 % CI]	97.5^th percentile [90 % CI]	Mean ± SD	Median	2.5^th percentile [90 % CI]	97.5^th percentile [90 % CI]
Tetrahydro-11-deoxycortisol	17.1 ± 10.1	15.5	2.7 [1.2, 6.9]	43.1 [35.1, 62.5]	23.2 ± 11.5	21.2	5.2 [5.1, 11.3]	56.2 [51.9, 56.3]	37.1 ± 27.4	31.6	8.9 [8.9, 11.4]	146 [110, 147]
Tetrahydro-11-deoxycorticosterone	12.5 ± 8.8	10.2	1.7 [0.9, 3.8]	40.1 [33.9, 46.6]	35.3 ± 102	16.1	4.1 [4.1, 5.9]	643 [466, 629]	588 ± 1681	31.6	6.1 [6.1, 14.7]	8789 [5075, 8875]
Corticosterone metabolites
Tetrahydroaldosterone	15.4 ± 10.7	12.0	2.7 [2.1, 5.0]	49.8 [36.5, 65.6]	18.2 ± 19.5	11.4	1.6 [1.6, 3.9]	114 [40.6, 116]	22.9 ± 16.6	18.2	2.1 [2.1, 7.1]	87.1 [55.1, 87.9]
Tetrahydro-11-dehydrocorticosterone	33.6 ± 23.7	26.7	3.9 [3.2, 10.9]	108 [88.5, 130]	35.1 ± 19.3	30.3	10.2 [10.1, 15.8]	89.4 [87.1, 89.4]	88.0 ± 88.9	56.1	13.4 [13.3, 27.4]	385 [371, 386]
Tetrahydrocorticosterone	23.1 ± 12.7	21.4	3.4 [3.0, 8.1]	57.8 [48.5, 63.4]	25.8 ± 13.2	22.3	3.3 [3.2, 8.5]	57.9 [55.0, 58.0]	83.0 ± 107.3	43.4	15.2 [15.1, 22.5]	586 [344, 591]
5α-Tetrahydro-corticosterone	51.5 ± 39.3	39.8	5.9 [4.3, 13.9]	189 [143, 194]	33.8 ± 21.6	30.0	1.7 [1.6, 9.8]	93.0 [91.7, 93]	59.0 ± 62.4	33.8	5.6 [5.6, 15.0]	304 [241, 306]