Table 6.
Postpartum urinary steroid hormone concentrations
| 6 weeks postpartum (n = 40) | ||||
|---|---|---|---|---|
| Steroid μg per mmol creatinine | Reference intervals | |||
| move to a separate row | Mean ± SD | Median | 2.5th percentile [90 % CI] | 97.5th percentile [90 % CI] |
| Androsterone | 130 ± 116 | 99.8 | 6.5 [6.2, 24.2] | 524 [482, 525] |
| Etiocholanolone | 180 ± 120 | 149 | 19.4 [19.3, 42.7] | 456 [423, 457] |
| 11-Oxo-Etiocholanolone | 51.0 ± 35.1 | 42.1 | 8.0 [8.0, 14.9] | 156 [149, 156] |
| 11β-Hydroxy-Androsterone | 77.5 ± 51.4 | 71.1 | 4.4 [4.2, 19.1] | 262 [149, 156] |
| 11β-Hydroxy-Etiocholanolone | 46.4 ± 36.6 | 38.3 | 4.8 [4.8, 9.3] | 161 [150, 161] |
| Dehydroepiandrosterone | 33.5 ± 57.1 | 10.4 | 0.8 [0.8, 2.7] | 291 [160, 294] |
| 5-Androstene-3β,17β-diol | 14.2 ± 15.1 | 9.4 | 0.4 [0.4, 1.6] | 68.0 [50.0, 68.4] |
| 5-Androstene-3β,17β-triol | 9.8 ± 21.5 | 3.1 | 0.2 [0.2, 0.6] | 113 [76.5, 114] |
| 16α-Hydroxy-dehydroepiandrostrerone | 46.8 ± 86.8 | 22.8 | 0.9 [0.9, 3.1] | 502 [212, 510] |
| 5-Androstene-3β,16α,17β-triol | 40.4 ± 45.9 | 29.6 | 3.7 [3.6, 9.5] | 271 [116, 275] |
| 5-Pregnene-3β,16α,17,20α-triol | 13.5 ± 12.5 | 10.7 | 0.4 [0.4, 1.3] | 59.5 [38.9, 60.0] |
| Testosterone | 3.7 ± 5.7 | 1.4 | 0.1 [0.1, 0.5] | 26.0 [22.9, 26.1] |
| 5α-Dihydrotestosterone | 2.5 ± 2.3 | 2.2 | 0.1 [0.1, 0.6] | 12.4 [8.2, 12.3] |
| Oestrogen metabolites | ||||
| Estriol | 119 ± 339 | 17.6 | 0.9 [0.9, 1.4] | 2011 [557, 2049] |
| 17β-Estradiol | 2.9 ± 9.6 | 0.5 | 0.1 [0.05, 0.1] | 58.7 [9.0, 60.0] |
| Progesterone precursor and metabolites | ||||
| Pregnenolone | 9.8 ± 13.4 | 4.7 | 0.2 [0.2, 0.7] | 52.5 [49.7, 52.2] |
| 17-Hydroxypregnanolone | 20.2 ± 41.4 | 9.9 | 0.9 [0.9, 2.4] | 257 [76.6, 262] |
| Pregnanediol | 257 ± 668 | 76.2 | 10.4 [10.3, 29.5] | 4052 [1173, 4126] |
| Pregnanetriol | 56.0 ± 49.7 | 44.3 | 5.9 [5.7, 20.8] | 297 [144, 301] |
| 11-Oxo-Pregnanetriol | 2.8 ± 3.4 | 1.6 | 0.4 [0.4, 0.7] | 17.7 [10.1, 17.8] |
| 11-Deoxysteroid metabolites | ||||
| Tetrahydro-11-deoxycortisol | 11.1 ± 8.6 | 9.8 | 0.7 [0.7, 3.0] | 43.1 [30.6, 42.8] |
| Tetrahydro-11-deoxycorticosterone | 28.2 ± 160 | 1.3 | 0.1 [0.1, 0.4] | 989 [27.0, 1014] |
| Corticosterone metabolites | ||||
| Tetrahydroaldosterone | 4.2 ± 4.6 | 2.6 | 0.5 [0.5, 1.1] | 21.9 [19.3, 21.9] |
| Tetrahydro-11-dehydrocorticosterone | 20.7 ± 23.5 | 14.6 | 0.4 [0.4, 3.3] | 139 [53.9, 142] |
| Tetrahydrocorticosterone | 23.8 ± 16.7 | 20.1 | 2.2 [2.2, 6.8] | 71.3 [69.3, 71.3] |
| 5a-Tetrahydrocorticosterone | 35.7 ± 28.1 | 28.8 | 1.7 [1.6, 6.3] | 143 [113, 143] |
| Cortisone metabolite | ||||
| Cortisone | 28.2 ± 20.1 | 23.4 | 1.0 [1.0, 10.3] | 101 [74.8, 101] |
| Tetrahydrocortisone | 397 ± 233 | 373 | 58.8 [58.2, 120] | 1034 [906, 1037] |
| α-Cortolon | 122 ± 117 | 90.5 | 18.1 [18, 33.5] | 707 [286, 718] |
| β-Cortolon | 30.6 ± 40.4 | 6.1 | 0.2 [0.2, 1.5] | 156 [141, 155] |
| 20α-Dihydrocortisone | 3.4 ± 2.7 | 2.7 | 0.2 [0.2, 1.1] | 13.5 [9.7, 13.6] |
| 20β-Dihydrocortisone | 9.2 ± 6.9 | 8.1 | 0.5 [0.4. 3.1] | 34.3 [24.5, 34.5] |
| Cortisol metabolites | ||||
| Cortisol | 20.8 ± 19.1 | 13.8 | 0.9 [0.8, 4.1] | 99.7 [66.7, 99.7] |
| Tetrahydrocortisol | 256 ± 153 | 243 | 30.7 [30.3, 80.3] | 723 [599, 726] |
| 5α-Tetrahydrocortisol | 97.1 ± 81.2 | 78.3 | 5.8 [5.4, 22.7] | 381 [302, 383] |
| α-Cortol | 41.1 ± 32.6 | 35.5 | 3.9 [3.8, 17.7] | 203 [98.2, 206] |
| β-Cortol | 55.3 ± 29.2 | 50.1 | 10.0 [9.9, 25.8] | 130 [114, 130] |
| 20α-Dihydrocortisol | 17.3 ± 22.6 | 9.3 | 0.2 [0.2, 3] | 127 [50.7, 127] |
| 6β-Hydroxycortisol | 149 ± 25.8 | 26.5 | 0.9 [0.9, 8.1] | 149 [77.9, 149] |
| 18-Hydroxycortisol | 322 ± 55.1 | 41.7 | 1.5 [1.4, 4.9] | 322 [130, 322] |