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. Author manuscript; available in PMC: 2015 Sep 3.
Published in final edited form as: J Mol Biol. 2008 Jul 2;381(5):1292–1306. doi: 10.1016/j.jmb.2008.06.072

Figure 1. Overall structure of GATA3 C-finger bound to DNA.

Figure 1

Figure 1

Figure 1

Crystal structures of GATA3 C-finger (purple, ribbon style) bound to the OPP (a) and ADJ (b) DNA (cyan, stick model); the zinc atom is shown in grey sphere. The same colour scheme is used throughout the illustration unless noted otherwise. The sequence of the DNA in each crystal structure is shown below the figure. The sequence of the OPP DNA in (a) is numbered for discussion in the text. The N- and C-terminus of the protein are labelled by bold letter N and C, respectively. The alternative C-terminal end of the right side GATA3 C-finger in (b) is indicated by C′. (c) C-alpha backbone superposition of the core zinc module between GATA3 C-finger (purple), chicken GATA1 C-finger (red), and the fungal AREA zinc finger (blue). The GATA3 C-finger bound to the consensus GATA site of the OPP DNA is used here. For clarity, only the DNA (stick model) from the GATA3 C-finger/DNA complex is shown.