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. 2015 Aug 28;10:5489–5503. doi: 10.2147/IJN.S87145

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© 2015 Lee et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Synthesis scheme for DendGDP.

Abbreviations: DendGDP, dendrimer-MPEG-DOX conjugate with GFLG peptide linkage; DendDP, dendrimer-MPEG-DOX conjugate; DOX, doxorubicin; MPEG, methoxy poly(ethylene glycol); EDAC, N-(3-dimethylaminopropyl)-N-ethylcarbodiimide hydrochloride; GFLG, Gly-Phe-Leu-Gly; TEA, triethylamine; NHS, N-hydroxysuccinimide.