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. 2015 Aug 28;10:5489–5503. doi: 10.2147/IJN.S87145

Figure 3.

Figure 3

Enzyme-sensitive drug release from DendDP and DendGDP nanoparticles.

Notes: Fluorescence intensity spectra (A) and near-infrared images (B) of DendGDP nanoparticles in the presence of CaB. Three milligrams of nanoparticles were incubated with CaB for 3 hours. (C) Release of DOX from the nanoparticles in the absence or presence of CaB (50 U).

Abbreviations: au, absorbance units; CaB, cathepsin B; DendGDP, dendrimer-MPEG-DOX conjugate with GFLG peptide linkage; DendDP, dendrimer-MPEG-DOX conjugate; DOX, doxorubicin; MPEG, methoxy poly(ethylene glycol); GFLG, Gly-Phe-Leu-Gly.