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. 2015 Aug 28;10:5489–5503. doi: 10.2147/IJN.S87145

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© 2015 Lee et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Anticancer activity of dendrimer nanoparticles.

Notes: (A) Anticancer activity of dendrimer nanoparticles and (B) near-infrared fluorescence images for CT26-bearing male nude BALB/c mice. DOX itself or DOX-conjugated dendrimer nanoparticles(5 mg/kg) were injected into the tail vein of each mouse. The major organs were removed from each mouse 48 hours after injection (Dotted circle: solid tumor). The data shown as the mean ± standard deviation (n=4). ***P<0.01; **P<0.001

Abbreviations: DendGDP, dendrimer-MPEG-DOX conjugate with GFLG peptide linkage; DendDP, dendrimer-MPEG-DOX conjugate; DOX, doxorubicin; MPEG, methoxy poly(ethylene glycol); GFLG, Gly-Phe-Leu-Gly.