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. Author manuscript; available in PMC: 2015 Sep 3.
Published in final edited form as: Behav Brain Res. 2011 Aug 18;227(2):410–417. doi: 10.1016/j.bbr.2011.08.002

Fig. 6.

Fig. 6

Multiple roles for HIF-1α in NSPC function and SVZ response to focal cerebral ischemia. Schematic depicting multiple potential roles for HIF-1α in NSPC function and SVZ response to focal cerebral ischemia. NSPC-HIF-1α is important for the maintenance of NSPCs in both SVZ and SGZ and modulates lineage fate of NSPCs in culture. NSPC-HIF-1α is also likely to be important in viability as well as proliferative and migratory responses of NSPCs following ischemic injury.