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Correlation of DHC/C ratios with hDHCR7 DNA and mRNA in brain. (A) Transgene (hDHCR7) copy number versus DHC/C shows an exponential relationship with a correlation coefficient of r2 = 0.82. (B) Relative hDHCR7 mRNA levels expressed as 2− ΔCt (Ct(hDHCR7)− Ct(mGAPDH)) versus DHC/cholesterol similarly shows an exponential relationship with a correlation coefficient of r2 = 0.73.
