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. 2015 Sep 4;14:127. doi: 10.1186/s12934-015-0312-7

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© Alkim et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Synthetic (blue) and natural (black) d-xylose assimilation pathways. In the synthetic pathway (d)-xylose is transformed to (d)-xylulose by endogenous xylose isomerase (XylA). (d)-xylulose-1-kinase (Khk-C) phosphorylates (d)-xylulose to obtain (d)-xylulose-1P, and (d)-xylulose-1-phosphate aldolase (Aldo-B) cleaves (d)-xylulose-1P into glycolaldehyde and DHAP. Ethylene glycol is produced via the action of an unknown endogenous aldehyde reductase.