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. 2015 Sep 3;10(9):e0137104. doi: 10.1371/journal.pone.0137104

Fig 3. Degree and pattern of enhancement as a function of tumor size.

Fig 3

a, Representative axial fat-saturated T1w MR images of mice given ACPPD-Gd (top row) and others imaged before (bottom row) and after gadobutrol (middle row) with comparable size tumors shown with the same window and level. Note that while ACPPD-Gd produced homogenous diffuse tumor enhancement (arrows), gadobutrol enhanced predominantly the tumor rim. Scale bar in each image = 5mm. b, Bar graph shows mean tumor enhancement ± SD for each contrast group as a function of tumor size groups. * indicates p<0.05, **p<0.01, ***p<0.001.