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. 2015 Sep 3;10(9):e0136667. doi: 10.1371/journal.pone.0136667

Table 5. Association between BI-RADS density measures and volumetric density in other studies. a .

BI-RADS 1/a BI-RADS 2/b BI-RADS 3/c BI-RADS 4/d Association measures
Volpara: percent dense volume N Mean (SD)
Gweon [35] 778 6.1 (0.9) 7.8 (2.3) 14.1 (5.8) 26.1 (5.2) % density vs. BI-RADS (Spearman’s ρ) = 0.765; VDG vs. BI-RADS (κw) = 0.54
N Median (IQR)
Current study 992 3.6 (3.1–4.4) 5.3 (4.3–6.8) 10.2 (8.1–13.2) 19.3 (15.1–23.5)
Jeffreys [36] 324 4 (3–5) 6 (4–8) 11 (8–16) 18.9 (15–22)
Seo [37] 193 5 (4–8) 9 (7–11) 14 (12–17) 21 (18–25) % density vs. BI-RADS (Spearman’s ρ) = 0.754; VDG vs. BI-RADS (ICC) = 0.757
Gubern-Mérida [38] 186 5.66 (5–6) 9 (8–11) 21 (18–24) 26.69 (24–29) % density vs. BI-RADS (Spearman’s ρ) = 0.79; VDG vs. BI-RADS (κw) = 0.40
Ko [39] 1129 VDG vs. BI-RADS (κ) = 0.26
Volpara: dense volume N Mean (SD)
Gweon [35] 778 33.7 (7.3) 40.7 (13.3) 50.7 (23.7) 63.8 (35.4)
N Median (IQR)
Current study 992 43 (37–52) 45 (35–57) 66 (50–88) 75 (50–102)
Jeffreys b [36] 324 38 (30–50) 50 (40–60) 60 (50–80) 80 (60–120)
Quantra: percent dense volume N Mean (SD)
Regini [40] 200 13.4 (3.6) 16.8 (4.2) 24.5 (7.2) 32.8 (8.3) % density vs. BI-RADS (Pearson’s r) = 0.99; Cut-off value BI-RADS3+4 = 21%
N Median (IQR)
Current study 992 8.5 (7.6–9.9) 11.0 (9.4–12.1) 16.1 (14.0–19.5) 23.1 (19.6–26.8)
N Median (range)
Ciatto c [41] 418 12.0 (7.0–19.0) 17.5 (10.0–32.0) 27.5 (16.0–47.0) 33.0 (24.5–50.5) Cut-off value BI-RADS3+4 = 22%
Quantra: dense volume N Median (IQR)
Current study 992 75 (56–112) 67 (44–89) 79 (55–110) 63 (44–97)

SD = standard deviation, IQR = inter-quartile range

a The results in italics were not published, but were based on estimates from the published boxplots.

b Values were rounded off.

c Also presented means, which were: 12.2 for BI-RADS 1, 18.0 for BI-RADS 2, 28.5 for BI-RADS 3, and 34.5 for BI-RADS 4.