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. 2015 Sep 3;10(9):e0136558. doi: 10.1371/journal.pone.0136558

Fig 1. Complement activation fragments are elevated in the plasma and urine of patients with FSGS.

Fig 1

Ba, Bb, C4a, and sC5b-9 fragments were measured in the (A) plasma and (B) urine of FSGS patients collected at the time of diagnosis. These fragments were also measured in samples from control subjects. Levels of all four complement activation fragments were increased in the plasma of FSGS patients. C4a and sC5b-9 were elevated in the urine of FSGS patients. The □ symbol indicates those FSGS patients with the full nephrotic syndrome (UPC > 3.5 g/g and serum albumin <3.0 g/dL). The groups were compared by ANOVA, and the statistical results shown are for FSGS versus the other indicated control groups. *P < 0.05, ***P < 0.001.