Table 2. Multivariate logistic regression analysis for the presence of CAA among children with CHD.
| Variables | aOR | (95%CI) b |
|---|---|---|
| Gender | ||
| Male | 1.43 | (1.29–1.59) |
| Female | 1.00 | |
| Age at CHD diagnosis a | ||
| Neonates | 3.25 | (2.43–4.35) |
| Infants | 5.31 | (3.97–7.09) |
| Toddlers & Preschools | 1.00 | |
| Follow-up period, years | ||
| 0–3 | 1.33 | (1.17–1.51) |
| 4–7 | 1.26 | (1.11–1.43) |
| ≧8 | 1.00 | |
| Other associated ECA | ||
| Nervous system | ||
| (+) | 2.71 | (2.25–3.28) |
| (-) | 1.00 | |
| Musculoskeletal system | ||
| (+) | 3.19 | (2.67–3.81) |
| (-) | 1.00 | |
| Eyes/ears/face/neck | ||
| (+) | 2.72 | (2.07–3.56) |
| (-) | 1.00 | |
| Cleft lip/palate | ||
| (+) | 2.28 | (1.81–2.89) |
| (-) | 1.00 | |
| Gastrointestinal system | ||
| (+) | 1.59 | (1.22–2.08) |
| (-) | 1.00 | |
| Urinary system | ||
| (+) | 1.06 | (0.74–1.52) |
| (-) | 1.00 | |
| Genital system | ||
| (+) | 1.76 | (1.36–2.26) |
| (-) | 1.00 | |
| Integument | ||
| (+) | 0.94 | (0.31–2.87) |
| (-) | 1.00 | |
| Chromosome | ||
| (+) | 2.51 | (2.08–3.04) |
| (-) | 1.00 |
Abbreviations: CHD, congenital heart disease; CAA, congenital airway anomaly; ECA, extracardiac anomaly; aOR, adjusted odds ratio; CI, confidence interval.
Odds ratios (OR) and 95% confidence intervals (CIs) are quoted.
aNeonate, newborn to ≤ 28 days of life; infant, >28 days but < 12 months; toddler & preschool, aged 1–5 years.
baOR adjusted for gender, age at CHD diagnosis, follow-up period and other ECA.