MB impedes the destruction of brain tissue. Brain sections were collected at 24 h after stroke. (A) Representative H&E staining in the cortex. The arrows indicate swelling cells. VC indicates vehicle control; and L, M and H, represent low, medium and high dose of MB, respectively. (B) Quantification the swelling cells. The percentage of the swelling cells was calculated as follows: swelling cells (%) = (the number of swelling cells/the total number of cells) × 100. MB obviously decreased the swelling cells caused by acute ischemia. n = 10; **P < 0.01 compared with the VC. Scale bar, 50 μm.