Table 1.

Lung transcriptional network genes physically located within the chromosome 7 Spir1 quantitative trait locus support interval.

Module	Gene symbol	Fold changea
IL17A/IL17F signaling	Zfp60	−2.32
NF-κB signaling	Zfp36	4.89
NF-κB signaling	Nfkbib	6.94
Complement system	B3gnt8	−2.04
Complement system	Papln	1.28
Interferon signaling	Ltbp4	−1.26
Interferon signaling	Fbln1	−1.95
Interferon signaling	Zfp365	−1.49
Interferon signaling	Zfp607	1.13
Interferon signaling	Mia3	−1.63
Interferon signaling	Fbxo17	−1.01
Interferon signaling	Sars2	0.87
Interferon signaling	Spred3	−1.09

^aFold change determined by comparing lung transcriptional profiles of 6-h pneumococcal pneumonia to uninfected samples.