Table 1.

Multicentric, Prospective Randomized Trial Details

Detail	Trial Name
	CLASICC*†	COLOR II†	COREAN
No. of patients	38119, 21	1,10323	34022
Recruitment	July 1996 to July 2002	January 2004 to May 2010	April 2006 to August 2009
No. of participating institutions	27	30	3
Country	United Kingdom	8 Countries	South Korea
Rectal segment, cm	All	0-15	0-9
Tumor stage	All	T1-3 (> 2 mm from MRF)	cT3N0-2

Abbreviations: CLASICC, Conventional Surgery Compared With Laparoscopic-Assisted Surgery in Treating Patients With Colorectal Cancer; COLOR II, Laparoscopic Versus Open Rectal Cancer Removal; COREAN, Randomized Prospective Trial for Laparoscopic vs Open Resection for Rectal Cancer; MRF, mesorectal fascia.

^*The CLASICC trial accrued a total of 794 patients (413 colon cancer; 381 rectal cancer).

^†Patients randomly assigned to open or laparoscopic surgery at a 1:2 ratio.