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. 2015 Sep 4;5:13568. doi: 10.1038/srep13568

Table 6. Cost to detect one colorectal neoplasia.

  Annual FIT scheme (N = 5,863) Colonoscopy scheme (N = 4,869) ICER with FIT as control
All
 Findings N Cost per finding N Cost per finding  
Screening Cost US$1,225,369 US$4,433,875  
  Adenoma 93 13,176 1,151 4,271 3,489
  AN 56 21,882 188 26,151 27,962
  CRC 10 122,537 14 357,172 922,762
  AN + CRC Stage 1 61 21,521 218 23,294 23,981
Moderate Risk (N = 4,940) (N = 3,805)  
Screening Cost US$1,026,448 US$3,792.324  
  Adenoma 70 14,664 839 4,520 3,597
  AN 46 22,314 116 32,692 39,513
  CRC 8 128,306 7 541,761 Dominated by FIT
  AN + CRC Stage 1 50 21,925 137 28,514 32,297
High Risk (N = 923) (N = 1,064)  
 Screening Cost US$199,184 US$1,119,993  
  Adenoma 20 9,959 312 3,590 3,153
  AN 10 19,918 72 15,555 14,852
  CRC 2 99,592 7 159,999 184,162
  AN + CRC Stage 1 11 19,708 79 14,720 13,919

FIT: Faecal Immunochemical Tests; CRC: Colorectal Cancer; ICER: Incremental Cost-Effectiveness Ratio; AN: advanced neoplasia.