Figure 8. Cartoon representation of the proposed σ^S-Crl interface.

The most likely model (Model E, Supplementary Fig. S11) is shown with Crl depicted in cyan and σ^S in wheat. The region containing the two salt bridges between σ^S and Crl is zoomed. In the zoom view, the side chain of the charged residues, involved in salt bridges, are colored as follows: in Crl, R51 in orange, D36 in magenta and in σ^S, R82 in green and the DPE motif in yellow.