Table 3. Correlation of DCE-MRI Parameters with Histologic Parameters of Two Contrast Agent Groups in 24-Hour Follow-Up Studies.
DCE-MRI Parameters | NF (n = 13) | MVD (n = 13) | ||
---|---|---|---|---|
1.857 ± 0.69 (P792, n = 7) | 30.8 ± 8.6 (P792, n = 7) | |||
2.0 ± 0.632 (Gd-DOTA, n = 6) | 34.2 ± 11.7 (Gd-DOTA, n = 6) | |||
Correlation Coefficient | P* | Correlation Coefficient | P* | |
Ktrans (min-1) | -0.21 | 0.351 | 0.26 | 0.287 |
iAUC (mmol/sec) | -0.25 | 0.282 | 0.21 | 0.41 |
*Spearman's correlation. DCE-MRI = dynamic contrast-enhanced magnetic resonance imaging, iAUC = initial area under gadolinium concentration-time curve until 60 seconds, MVD = microvessel density, NF = necrotic fraction