Table 1. Demographic and characteristic data of cirrhotic patient groups.
Parameters | HCC+ (n=61) | HCC− (n=78) | P |
---|---|---|---|
Age (mean±s.d.; years) | 56.5±8.6 | 50.2±11.6 | 0.006 |
Gender, female (n) | 8 | 24 | 0.01 |
Child–Pugh category A/B/C (n) | 25/19/11a | 24/17/35a | 0.03 |
MELD score | 11.8±5.0 | 22.4±8.6 | <0.001 |
Serum CRP (mg l−1) | 15.8±21.8 | 22.9±26.1 | 0.009 |
Serum neopterin (nmol l−1) | 22.2±21.0 | 58.1±76.8 | <0.001 |
Previous transplantation (n) | 2 | 15 | 0.004 |
Pre-tx encephalopathy (n) | 8 | 33 | <0.001 |
Viral IgG statusa | |||
HBV-Ab+ (n) | 11 | 6 | 0.06 |
HCV-Ab+ (n) | 20 | 9 | 0.002 |
CMV-Ab+ (n) | 37 | 44 | 0.61 |
Original liver disease | |||
Hepatitis/alcoholic/others (n) | 25/19/17 | 15/22/41 | 0.01 |
Abbreviations: Ab=antibody; CMV=cytomegalovirus; CRP=C-reactive protein; HBV=hepatitis B virus; HCC=hepatocellular carcinoma; HCV=hepatitis C virus; IgG=immunoglobulin; MELD=model for end-stage liver disease; Pre-Tx=pretransplant. Mann–Whitney U-test, chi square, Fisher exact and Kruskal–Wallis tests were used. P-values<0.05 after Bonferroni correction were considered significant and are in bold.
Some missed data.