Table 2. Univariate survival analyses.
| Median cancer-specific survival (months) | P-value | |
|---|---|---|
| Age (years)* (n=218) | 0.0004 | |
| Multifocality (n=207) | NS | |
| No | 7.9 | |
| Yes | 10.6 | |
| Date of surgery* (n=218) | NS | |
| Surgical resection (n=203) | 0.002 | |
| Partial | 8.4 | |
| Complete | 13.1 | |
| Adjuvant therapy (n=168) | 10−5 | |
| Radiotherapy | 10.6 | |
| Radiotherapy+temozolomide | 14.9 | |
| IGFI LI* (n=212) | NS | |
| IGFII LI* (n=204) | NS | |
| IGF-IR LI* (n=218) | 0.046 | |
| IGF-IIR LI* (n=213) | NS | |
|
Binary scores | ||
| IGFI (n=212) | NS | |
| Positive | 8.7 | |
| Negative | 10.5 | |
| IGFII (n=204) | NS | |
| Positive | 8.8 | |
| Negative | 9.3 | |
| IGF-IR (n=218) | 0.020 | |
| Positive | 9.0 | |
| Negative | 11.6 | |
| IGF-IIR (n=213) | NS | |
| Positive | 10.3 | |
| Negative | 9.2 | |
Abbreviations: IGF=insulin-like growth factor; LI=labelling index; NS=not significant. Continuous variables were analysed using the univariate Cox regression (see asterisk (*)). The other binary variables were analysed using the log-rank test. For these latter variables, each category is characterised by the median cancer-specific survival time (in months). For IGFI, IGFII, IGF-IR and IGF-IIR, the cases labelled as positive correspond to LI⩾1% and those labelled as negative to LI<1%. The n values indicate the total number of cases taken into account in the univariate analyses (excluding the missing values and certain non-standard clinical categories that are detailed in Table 1).