Table 3. Cox regression model (n=167).

Model/P-value	Prognostic factors	Hazard ratio	95% CI	P-value
<10−5	Age	1.02	1.01–1.04	0.003
	Complete resection	0.67	0.45–0.98	0.039
	Radiotherapy+temozolomide	0.35	0.17–0.70	0.003
	IGF-IR positive	1.65	1.10–2.47	0.016

Abbreviations: CI=confidence interval; IGF=insulin-like growth factor. The ‘Model/P-value' indicates the overall level of significance of the multivariate model. With the exception of ‘Age', which is a quantitative variable, all of the others are binary. Resection distinguishes between partial and complete, adjuvant treatment between radiotherapy and radiotherapy+temozolomide and IGF-IR between positive (LI⩾1%) and negative (LI<1%). The individual P-values represent the levels of significance of the independent contributions of each factor.