Table 1. Systemic treatment protocols (A–E) grouped by menopausal status.
| Group | Protocol | Treatment | Details |
|---|---|---|---|
| Premenopausal (N=751) | A | No adjuvant treatment | |
| B | CT+ET | 7 cycles of CEF+tamoxifen (20 mg)a | |
| D | CT | 7 cycles of CEF | |
| Postmenopausal (N=1138) | A | No adjuvant treatment | |
| C | ET | Tamoxifen (20 mg)+exemestane (25 mg)b | |
| E | CT | 7 cycles of CMF |
Abbrevaitions: CEF=cyclophosphamide, epirubicin, and fluorouracil; CMF=cyclophosphamide, methotrexate, and fluorouracil; CT=chemotherapy; ET=endocrine treatment.
a
Duration of 5 years.
b
Sequential treatment with a duration of 2.5 years of Tamoxifen followed by 2.5 years of Exemestane.