Table 1.
BMI Group | WC Group | ||||
---|---|---|---|---|---|
Normal | Overweight | Obese | Non-risk | At-risk | |
|
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Number of subjects | 34 | 26 | 42 | 52 | 50 |
Sex, % Female | 71 | 62 | 69 | 60 | 76* |
Age, years | 43±2 | 46±3 | 49±2 | 43±2 | 50±2 |
Weight, kg | 64±1 | 76±2* | 102±2*# | 68±2 | 98±3* |
Height, cm | 169±1 | 166±2 | 167±1 | 167±1 | 168±1 |
BMI, kg/m2 | 22±0.3 | 28±0.3* | 37±0.8*# | 24±0.5 | 35±0.9* |
Waist, cm | 79±1 | 90±2* | 112±2*# | 82±1 | 109±2* |
Triglycerides, mg/dL | 65±5 | 125±15 | 158±22* | 88±9 | 150±19* |
HDL, mg/dL | 62±3 | 49±3* | 48±3* | 57±3 | 49±2* |
Glucose, mg/dL | 92±2 | 97±2 | 100±1* | 95±1 | 98±2 |
Insulin, μIU/mL | 4±0.4 | 10±1.3* | 13±1.0* | 6±0.7 | 12±1* |
HOMA-IR | 1.01±0.12 | 2.42±0.37* | 3.19±0.29* | 1.48±0.19 | 3.05±0.27* |
Tg/HDL | 1.17±0.13 | 3.18±0.55* | 3.81±0.58* | 1.91±0.31 | 3.57±0.49* |
bSBP, mmHg | 112±2 | 119±2 | 128±2*# | 115±2 | 126±2* |
bPP, mmHg | 40±2 | 43±2 | 49±2* | 42±1 | 47±2 |
cSBP, mmHg | 103±2 | 109±2 | 117±2*# | 105±2 | 116±2* |
cPP, mmHg | 31±2 | 33±2 | 37±2* | 31±1 | 37±2* |
cIMT, mm | 0.61±0.02 | 0.67±0.03 | 0.69±0.02* | 0.62±0.02 | 0.70±0.02* |
CDd, mm | 0.57±0.01 | 0.57±0.01 | 0.61±0.01*# | 0.57±0.01 | 0.60±0.01* |
cCSA mm2 | 10.5±0.3 | 11.4±0.5 | 12.7±0.5* | 10.7±0.3 | 12.6±0.4* |
PWVcf, m/s | 6.8±0.26 | 7.3±0.3 | 7.9±0.25* | 6.8±0.19 | 8.0±0.23* |
HTN,% | 3 | 28 | 54*# | 8 | 54* |
EF. % | 63±1 | 59±1 | 60±1 | 62±1 | 60±1 |
Medications | |||||
Diuretics, % | 1 (3) | 0 (0) | 5 (12) | 3 (6) | 7 (14) |
B-blockers, % | 0 (0) | 2 (8) | 5 (12) | 2 (4) | 5 (10) |
ACEI/ARB, % | 0 (0) | 1 (4) | 8 (19)*# | 0 (0) | 9 (18)* |
Ca2+ blockers, % | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) |
Statins, % | 2 (6) | 1 (4) | 7 (16) | 3 (6) | 7 (14) |
BMI: body mass index = normal BMI <25 kg/m2, overweight BMI 25-29.9 kg/m2, obese BMI>30 kg/m2; WC: waist circumference = Non-risk group, male< 102 cm, female <88 cm; at-risk group, male≥ 102 cm, female ≥88 cm
Abbreviations: b = brachial; c = central; HDL: high density lipoprotein; Tg: triglycerides; HOMA-IR: homeostatic model assessment Insulin Resistance; cIMT, carotid intima medial thickness; cCSA, common carotid cross sectional area; CDd, carotid diameter in diastole; PWVcf, carotid-femoral pulse wave velocity; SBP, systolic pressure; PP, pulse pressure; HTN: hypertension status; EF; ejection fraction; ACEI: angiotensin-converting enzyme inhibitors; ARB: angiotensin II receptor blockers; Ca2+: calcium channel blockers. For BMI groups
p<0.05 vs normal,
p<0.05 vs. overweight; for WC group,
p<0.05 vs. non-risk.