(A) Proliferation of tumor EC 3 days after withdrawal of VEGF (No VEGF), RT (6 Gy), and/or low dose doxorubicin (Dox, 0.005 μM). (B) Colony formation of tumor EC 14 days after withdrawal of VEGF (No VEGF), RT (0, 2, 4 and 6 Gy), and/or low dose doxorubicin (Dox, 0.005 μM). (C) Immunofluorescence photos of Comet assay, γH2AX expression, and cleaved caspase 3. Experiments were performed in normoxia (21% O2) and hypoxia (1% O2). *p<0.05 compared to all other groups.