Table 1.
% of pregnancies | Mothers who drank alcohol during the pregnancy | |||||
---|---|---|---|---|---|---|
% drinking alcohol | Univariate analysis | Multivariable model(a) | ||||
Variables | RR (95 % CI) | p-value | ARR (95 % CI) | p-value | ||
Total (n = 33006)(b) | 100.0 | 34.1 | ||||
Mother's age in years (n = 32985) | < 0.001 | 0.001 | ||||
17 or younger | 2.6 | 17.4 | 0.41 (0.35 – 0.48) | 0.83 (0.66 – 1.03) | ||
18 – 25 | 38.9 | 28.3 | 0.67 (0.64 – 0.70) | 0.93 (0.86 – 1.00) | ||
26 – 35 | 48.2 | 37.9 | 0.89 (0.85 – 0.93) | 1.02 (0.97 – 1.08) | ||
36 or older | 10.3 | 42.5 | 1.00 | 1.00 | ||
Number of previous pregnancies (n = 32029) | < 0.001 | < 0.001 | ||||
0 | 37.0 | 26.7 | 0.65 (0.62 – 0.68) | 0.82 (0.77 – 0.87) | ||
1 | 26.4 | 36.2 | 0.88 (0.84 – 0.92) | 1.00 (0.95 – 1.05) | ||
2 | 17.3 | 41.8 | 1.02 (0.97 – 1.06) | 1.09 (1.04 – 1.15) | ||
3 or more | 19.3 | 41.1 | 1.00 | 1.00 | ||
Mother's tribe (n = 32961) | < 0.001 | < 0.001 | ||||
Chagga | 55.8 | 45.2 | 2.07 (1.99 – 2.16) | 1.34 (1.27 – 1.41) | ||
Pare | 12.6 | 17.3 | 0.79 (0.74 – 0.86) | 0.92 (0.84 – 1.01) | ||
Maasai | 1.0 | 6.6 | 0.31 (0.21 – 0.45) | 0.88 (0.57 – 1.35) | ||
Other | 30.6 | 21.8 | 1.00 | 1.00 | ||
Mother's religion (n = 32783) | < 0.001 | < 0.001 | ||||
Catholic | 38.6 | 53.6 | 3.62 (3.41 – 3.84) | 2.91 (2.69 – 3.14) | ||
Protestant | 40.0 | 25.9 | 1.75 (1.64 – 1.87) | 1.59 (1.47 – 1.72) | ||
Muslim | 21.4 | 14.8 | 1.00 | 1.00 | ||
Mother's Body Mass Index before pregnancy (n = 25417) | < 0.001 | < 0.001 | ||||
< 18.5 Underweight | 5.2 | 23.8 | 0.58 (0.50 – 0.67) | 0.71 (0.62 - 0.82) | ||
18.5 – 24.9 Normal weight | 56.8 | 33.7 | 0.82 (0.73 – 0.91) | 0.86 (0.77 - 0.96) | ||
25.0 – 29.9 Overweight | 26.9 | 41.5 | 1.01 (0.90 – 1.13) | 0.95 (0.85 - 1.06) | ||
30.0 – 34.9 Obese Class 1 (Moderately Obese) | 9.3 | 44.3 | 1.07 (0.95 – 1.21) | 0.97 (0.87 - 1.09) | ||
≥ 35.0 Obese Class 2 (Severely Obese) | 1.8 | 41.3 | 1.00 | 1.00 | ||
Mother's height (n = 29314) | < 0.001 | 0.001 | ||||
< 150 cm | 5.5 | 26.7 | 0.67 (0.60 – 0.73) | 0.81 (0.73 – 0.90) | ||
150 – 159 cm | 41.3 | 33.8 | 0.84 (0.79 – 0.89) | 0.92 (0.86 – 0.97) | ||
160 – 169 cm | 45.9 | 36.8 | 0.92 (0.87 – 0.97) | 0.91 (0.86 – 0.97) | ||
≥170 cm | 7.3 | 40.2 | 1.00 | 1.00 | ||
Current residence (n = 32913) | < 0.001 | 0.001 | ||||
Urban area | 52.2 | 34.4 | 1.00 (0.97 – 1.04) | 1.07 (1.03 – 1.11) | ||
Semiurban area | 4.8 | 28.5 | 0.83 (0.77 – 0.90) | 1.01 (0.92 – 1.11) | ||
Rural area | 43.0 | 34.3 | 1.00 | 1.00 | ||
HIV status (n = 33006) | < 0.001 | < 0.001 | ||||
Negative | 59.4 | 28.9 | 0.69 (0.67 – 0.71) | 0.91 (0.87 – 0.95) | ||
Positive | 3.9 | 39.3 | 0.94 (0.87 – 1.00) | 1.11 (1.01 – 1.21) | ||
Unknown | 36.7 | 42.0 | 1.00 | 1.00 | ||
Father's age (n = 32745) | < 0.001 | < 0.001 | ||||
25 or younger | 15.1 | 25.7 | 0.60 (0.56 – 0.65) | 0.82 (0.74 – 0.91) | ||
26 – 35 | 55.2 | 33.0 | 0.77 (0.73 – 0.83) | 0.85 (0.79 – 0.92) | ||
36 – 45 | 25.6 | 40.5 | 0.95 (0.89 – 1.02) | 0.93 (0.86 – 1.00) | ||
46 or older | 4.2 | 42.6 | 1.00 | 1.00 | ||
Father's tribe (n = 32835) | < 0.001 | < 0.001 | ||||
Chagga | 50.3 | 45.3 | 1.85 (1.79 – 1.92) | 1.24 (1.19 – 1.30) | ||
Pare | 12.5 | 19.2 | 0.78 (0.73 – 0.84) | 0.94 (0.87 – 1.03) | ||
Maasai | 1.4 | 13.6 | 0.56 (0.44 – 0.70) | 1.00 (0.78 – 1.30) | ||
Other | 35.8 | 24.5 | 1.00 | 1.00 | ||
Year (n = 33006) | < 0.001 | < 0.001 | ||||
2000 | 4.8 | 49.5 | 2.30 (2.12 – 2.49) | 1.88 (1.68 – 2.11) | ||
2001 | 10.1 | 44.7 | 2.08 (1.93 – 2.24) | 1.86 (1.68 – 2.07) | ||
2002 | 9.1 | 44.9 | 2.09 (1.94 – 2.25) | 1.86 (1.68 – 2.07) | ||
2003 | 8.1 | 44.2 | 2.06 (1.90 – 2.22) | 1.72 (1.55 – 1.91) | ||
2004 | 8.5 | 39.1 | 1.82 (1.68 – 1.97) | 1.58 (1.42 – 1.76) | ||
2005 | 8.6 | 34.9 | 1.62 (1.49 – 1.76) | 1.49 (1.34 – 1.66) | ||
2006 | 8.9 | 32.0 | 1.49 (1.37 – 1.62) | 1.46 (1.31 – 1.62) | ||
2007 | 9.8 | 28.5 | 1.33 (1.22 – 1.44) | 1.25 (1.12 – 1.40) | ||
2008 | 10.9 | 26.2 | 1.22 (1.12 – 1.33) | 1.20 (1.08 – 1.34) | ||
2009 | 10.8 | 23.3 | 1.08 (0.99 – 1.18) | 1.02 (0.92 – 1.15) | ||
2010 | 10.4 | 21.5 | 1.00 | 1.00 |
(a)In the multivariable analyses all predictors have been adjusted for mother's age, mother's occupation, mother's tribe, mother's religion, mother's body mass index, mother's height, previous pregnancies, mother's current residence, mother's childhood residence, father's age, father's tribe, year of delivery, drinking water source, boiling of drinking water, mother's age at marriage and mother's HIV-status
(b) For all the predictors one data entry per pregnancy has been included