Table 3.
Genotypic and allelic association analysis of VDR single-nucleotide polymorphisms between NWNA and CUWA
| SNP | Genotypic association | Allelic association | |||||||
|---|---|---|---|---|---|---|---|---|---|
| NWNA (n, %) | CUWA (n, %) | χ 2 | P value | NWNA (n, %) | CUWA (n, %) | OR (95 % CI) | P value | ||
| BsmI | |||||||||
| BB | 127 (20.1 %) | 11 (17.5 %) | |||||||
| Bb | 327 (51.8 %) | 32 (50.8 %) | B | 581 (46 %) | 54 (42.8 %) | ||||
| bb | 177 (28.1 %) | 20 (31.7 %) | 0.492 | 0.782 | b | 681 (54 %) | 72 (57.2 %) | 0.88 (0.61–1.27) | 0.513 |
| TaqI | |||||||||
| TT | 224 (35.6 %) | 28 (45.9 %) | |||||||
| Tt | 325 (51.6 %) | 20 (32.8 %) | T | 773 (61.3 %) | 76 (62.3 %) | ||||
| tt | 81 (12.9 %) | 13 (21.3 %) | 8.492 | 0.014 | t | 487 (38.7 %) | 46 (37.7 %) | 1.04 (0.71–1.53) | 0.922 |
| ApaI | |||||||||
| AA | 232 (36.7 %) | 19 (31.1 %) | |||||||
| Aa | 312 (49.3 %) | 34 (55.7 %) | A | 776 (61.3 %) | 72 (59 %) | ||||
| aa | 89 (14.1 %) | 8 (13.1 %) | 0.966 | 0.617 | a | 490 (38.7 %) | 50 (41 %) | 0.91 (0.62–1.33) | 0.628 |