Table 1. Clinical characteristics of the hospitalized patients from the two outbreaks#.
| Characteristic |
Value* |
|
|---|---|---|
| Xiangyang outbreak (n = 321) | Jingmen outbreak (n = 42) | |
| Symptoms or signs | ||
| Fever | ||
| Any-no. (%) | 319 (99.4) | 42 (100.0) |
| Subgroup-no. (%) | ||
| 37.3–38.0 °C | 10 (3.1) | 0 |
| 38.1–39.0 °C | 131 (40.8) | 20 (47.6) |
| >39.0 °C | 178 (55.5) | 22 (52.4) |
| Maximal temperature (°C), mean | 39.2 ± 0.6 | 39.4 ± 0.7 |
| Duration of fever, median (range), days | 4.0 (1–20) | 4.0 (2–11) |
| Cough | 304 (94.7) | 40 (95.2) |
| Throat congestion | 296 (92.2) | 36 (85.7) |
| Sore throat | 246 (76.6) | 32 (76.2) |
| Sputum production -no./total no. (%) | 234/321 (72.9) | 34/42 (81.0) |
| Yellow sputum | 145/234 (62.0) | 24/34 (70.6) |
| White sputum | 89/234 (38.0) | 10/34 (29.4) |
| Blood-streaked sputum | 28/234 (12.0) | 6/34 (17.6) |
| Swelling of tonsils | 211 (65.7) | 24 (57.1) |
| Fatigue | 139 (43.3) | 21 (50.0) |
| Pharyngeal lymphoid follicular hyperplasia | 126 (39.3) | 15 (35.7) |
| Purulent exudate on the tonsil | 102 (31.8) | 12 (28.6) |
| Rhinorrhea | 79 (24.6) | 9 (21.4) |
| Myalgia | 76 (23.7) | 8 (19.0) |
| Headache | 64 (19.9) | 8 (19.0) |
| Dizziness | 61 (19.0) | 5 (11.9) |
| Shortness of breath | 54 (16.8) | 8 (19.0) |
| Chest pain | 51 (15.9) | 9 (21.4) |
| Diarrhea | 30 (9.3) | 5 (11.9) |
| Nasal congestion | 29 (9.0) | 2 (4.8) |
| Chill | 23 (7.2) | 2 (4.8) |
| Enlargement of lymph nodes | 20 (6.2) | 4 (9.5) |
| Abdominal pain | 19 (5.9) | 3 (7.1) |
| Bronchitis | 18 (5.6) | 1 (2.4) |
| Nausea | 12 (3.7) | 5 (11.9) |
| Vomiting | 8 (2.5) | 1 (2.4) |
| Palpitation | 3 (0.9) | 1 (2.4) |
| Submandibular lymphadenitis | 3 (0.9) | 0 |
| Tinnitus, earache | 3 (0.9) | 0 |
| Skin rash | 2 (0.6) | 1 (2.4) |
| Convulsion, coma | 2 (0.6) | 0 |
| Testicular pain | 2 (0.6) | 0 |
| Clinical outcome | ||
| Hospitalization, no./total no. (%) | 321/858 (37.4) | 42/88 (47.7) |
| Time from illness onset to hospitalization, median (range), days | 3.0 (1–36) | 3.0 (1–7) |
| Duration of hospitalization, median (range), days | 10.0 (6–25) | 9.0 (7–25) |
| Pneumonia, no./total no. (%) | 108/321 (36.2) | 16/42 (38.1) |
| Admission to an intensive care unit | 37/108 (34.3) | 4/16 (25.0) |
| Heart injury | 14/108 (13.0) | 2/16 (12.5) |
| Liver injury | 11/108 (10.2) | 3/16 (18.8) |
| Gallbladder injury | 3/108 (2.8) | 1/16 (6.3) |
| Meningitis irritation | 2/108 (1.9) | 0 |
| Secondary infections | 10/108 (9.3) | 2/16 (12.5) |
#In this study 256 patients were confirmed as HAdV-7 positive infections among the 321 hospitalized patients by PCR and viral culture.
*In this study continuous variables were summarized as means (±SD) or medians (range).