Table 4.
MMP and TIMP activities in the follicular fluid between high and low D5 GB embryo groups
| High D5 GB group (D5 GB ≥ 50 %) | Low D5 GB group (D5 GB < 50 %) | P value | |
|---|---|---|---|
| Number of patients | 59 | 91 | |
| Estradiol (pg/ml) | 2937 ± 1362 | 2541 ± 1715 | NS |
| Progesterone (ng/ml) | 0.83 ± 0.76 | 0.68 ± 0.36 | NS |
| MII oocytes ratio (%) | 89.7 ± 14.6 | 92.4 ± 15.0 | NS |
| 2PN embryos ratio (%) | 77.0 ± 21.0 | 67.7 ± 25.5 | < 0.05 |
| D5 GB embryos ratio (%) | 72.4 ± 16.3 | 11.8 ± 16.5 | < 0.001 |
| MMP-2 (Arbitrary units/μl) | 17.2 ± 4.3 | 19.1 ± 4.5 | NS |
| MMP-9 (Arbitrary units/μl) | 2.25 ± 0.66 | 2.04 ± 0.63 | NS |
| TIMP-1 (ng/ml) | 114 ± 30 | 120 ± 36 | NS |
| TIMP-2 (ng/ml) | 54.9 ± 14.8 | 54.3 ± 16.1 | NS |
MII Metaphase II, 2PN Two pronuclei, D5 GB Good-quality blastocysts on day 5, MMP Matrix metalloproteinase, TIMP Tissue inhibitor of matrix metalloproteinase
Values are expressed as the means ± SD. P values are comparisons between the high and low D5 GB embryo groups by ANOVA.; NS: no statistical significance (i.e., P > 0.05)