Fig. 2.

Slamf6 ^−/− mice are equally resistant to C. rodentium-induced colitis as WT mice. WT and Slamf6 ^−/− mice were infected by oral gavage of 2×10⁹ C. rodentium bacteria. The animals were checked daily and sacrificed when their weight dropped below 80% of their starting weight. (A) The weight of individual mice was measured every 4 days and represented as a percentage of their weight on the day of infection. (B) Survival of infected WT and Slamf6 ^−/− mice. (C) C. rodentium counts of fecal pellets that were obtained directly from mice every 3 days. Serial dilutions were made in PBS and plated on MacConkey plates. Counted bacterial colonies are represented as CFU per g feces.