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Spontaneous Ca2+ elevation and genesis of a PVC in the absence of SCRs in the PS. (A) Spatial distribution of Cas at time instants: t1 = 0 ms, the start of pacing pause; t2 = 25 ms; t3 = 120 ms, the time of maximum rate of rise of Cas at focal site, and t4 = 156 ms, time of maximum rate of rise of the triggered AP. (B) Cas transient recorded at the ectopic focus. (C) Boxplots illustrating distribution of Cas over the ventricles at time instants t1–t4.
