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Distribution of gene-level P-values. (A) Density plot of gene level P-values within CD-associated regions (n = 1328) as defined by Jostins et al. (1), compared with all other genes (n = 23 134). (B) Q–Q plot of observed gene-level P-values compared with expected gene-level P-values. Observed P-values of 0.05 and 3E−6 are indicated by gray dashed lines.
