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Effect of RAD1901 on mouse survival in an intracranial MCF-7 tumor model. Female nude mice were implanted with 1×106 MCF-7 cells intracranially. Five days after tumor cell implantation (designated as day 1 of the study), mice were randomized into three groups of 12 animals each and treated with vehicle, fulvestrant (0.5 mg/animal daily), or RAD1901 (120 mg/kg daily).
