FIG 5.

Comparison of doubling times of mutant strains in the presence or absence of U. Mutants were grown in buffered PYE medium to early exponential phase and were either untreated (black bars) or spiked with 350 μM uranyl nitrate (gray bars). Doubling times were estimated based on OD₆₀₀ values during growth. Error bars represent standard deviations from three biological replicates. Mutants showing a significant increase in doubling time compared to that of the wild type (wt) under the same conditions (without or with U) are highlighted with asterisks (*, P < 0.02; **, P < 0.0001).