FIG 5.

Heat map representation of RNA-Seq expression changes of genes involved primarily in extracellular nutrient uptake and energy metabolism in gene islands differentially regulated by CovS. The fold changes in expression of each gene between CovS⁺ and CovS⁻ at LP and SP and between SP and LP for both the CovS⁺ and CovS⁻ phenotypes are represented with gradient colors. The genes falling into the same gene islands are clustered. The functional classifications of the gene islands are grouped into four broad categories of nutrient utilization: sugars and glycerol (A); biotin, heme iron, and inorganic molecules (B); peptides, amino acids, and nucleosides (C); and energy metabolism and production (D). An asterisk indicates that the classification is putative.