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Acetyl-phosphate accumulation results in restricted growth of M. tuberculosis. The M. tuberculosis H37Rv wild type (WT) and the Δpta mutant were cultivated under fast-growth conditions for 10 days. Growth was analyzed in the presence of 20 mM acetate (Ac) or 20 mM acetyl-phosphate (AP). The data represent the mean from three independent experiments; error bars indicate the SD.
