Table 1.
Summary of TraceRNA Algorithms
Algorithm or Database | Output | Function of Algorithm |
---|---|---|
miRTarBase | Experimentally verified miRNA:target interactions | Identify validated miRNAs |
SVMicrO | Scores of miRNA-gene binding prediction by using a large number of binding site and 3’UTR features | Predict miRNAs binding |
BCMicrO | Scores of miRNAs-genes binding predictions by fusion of 6 algorithms | |
SiteTest | Scores of miRNAs-genes binding predictions using 3’UTR features | |
ceRNA-SVMicrO ceRNA-BCMicrO ceRNA-SiteTest |
Scores for predicted ceRNAs by sequence-pairing | Predict ceRNAs by sequence-pairing |
Expression Correlation | Pearson correlation of GOI and predicted ceRNAs by sequence-pairing | Calculate correlation between predicted ceRNAs by sequence-pairing |
SeqExp Fusion (Borda merging method) | Scores from fusing sequence-level predictions and expression correlation | Fuse sequence-level predictions and co-expression |
ceRNA-Net | List of gene pairs (nodes) and scores of their directed interactions | Discover regulatory networks |