Figure 7.

Estimated components of model (8) with ±2 pointwise standard errors, using Ivanescu et al. (2012). Coefficient surfaces are color-coded for sign and pointwise significance (95%): blue if sig. < 0, light blue if < 0, light red if > 0, red if sig. > 0. Top row, left to right: mean FA-CCA for healthy (blue, dotted) versus MS (red, solid) females; mean FA-CCA for female (purple, solid) and male (green, dotted) MS patients; estimated effect of age-at-visit $\widehat{\nu }(u,t)$. Bottom row, left to right: Estimated coefficient surfaces ${\widehat{\beta }}_{1,0}(s,t)$, ${\widehat{\beta }}_{1,1}(s,t)$, ${\widehat{\beta }}_{2,0}(r,t)$, ${\widehat{\beta }}_{2,1}(r,t)$.