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. 2015 Sep 4;10(9):e0137257. doi: 10.1371/journal.pone.0137257

Fig 2. Scavenging ROS reversed the apoptotic phenotype observed in HIF-1α knockdown cells under hypoxia.

Fig 2

(A) The ROS levels were estimated using the KD and SC cells under hypoxia for 0 h to 72 h. (B) The ROS level was analyzed in hypoxic KD cells with or without 5 mM NAC treatment for 0 to 72 h. (C) The cell death rate was assessed in KD cells with or without NAC under normoxia (C) and hypoxia (D) for 0 h to 96 h. KD-NAC(-): NAC-untreated KD cells, KD-NAC(+): NAC-treated KD cells. *: p<0.05, ***: p<0.001.