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In this graph we show the activity of the CDKA;1-CYCD3;1 and the CDKA;1-CYCB1;1 complexes as a function of the amount of cyclins, and KRP1 inhibitor. The CDK-cyclin activity is the limiting factor to pass the G1/S and the G2/M checkpoints. A little more than two complete CC are shown (upper horizontal axis) to confirm that oscillations are maintained.
