Figure 7.
Expression of hydroxyproline in KF supernates measured by ELISA.
Notes: Using a human hydroxyproline ELISA kit, we found that the expression of hydroxyproline in KF supernates was downregulated in all inhibitors’ groups. Chymostatin (1,000 μmol/L), chymostatin (1,000 μmol/L) + captopril (1,000 μmol/L), and valsartan (10−5 mol/L) significantly depressed the expression of hydroxyproline (P<0.05). All values are mean ± SD. *P<0.05, **P<0.01 represent the hydroxyproline level compared to the KFs group.
Abbreviations: KFs, keloid fibroblasts; ELISA, enzyme-linked immunosorbent assay; SD, standard deviation.