Table 1.
Summary of single Boltzmann function parameters in control versus IL-1β treated medium-diameter DRG neurons
| Parameter | Control | IL-1β |
|---|---|---|
| INa activation V1/2 (mV) | −32.5 ± 2.6 mV (9) | −41.4 ± 2.2 mV (11)* |
| INa activation slope factor (mV) | 3.6 ± 1.1 mV (9) | 3.3 ± 0.5 (11) |
| INa steady-state fast inactivation V1/2 (mV) | −61.3 ± 1.9 mV (7) | −62.0 ± 0.9 (11) |
| INa steady-state fast inactivation slope factor (mV) | 7.7 ± 0.8 mV (7) | 8.8 ± 0.9 (11) |
| INa steady-state slow inactivation V1/2 (mV) | −62.4 ± 6.1 mV (5) | −57.8 ± 2.5 (5) |
| INa steady-state slow inactivation slope factor (mV) | 13.5 ± 1.9 mV (5) | 13.6 ± 1.1 (5) |
| IBa inactivation V1/2 (mV) | −45.3 ± 13.8 mV (7) | −78.8 ± 5.9 (13)* |
| IBa slope factor (mV) | 15.0 ± 2.2 mV (7) | 17.8 ± 1.4 (13)† |
| IH steady-state activation V1/2 (mV) | −70.7 ± 2.7 mV (9) | −65.9 ± 5.1 mV (10) |
| IH slope factor (mV) | 12.2 ± 1.6 mV (9) | 10.7 ± 1.7 (10) |
Values are means ± SEM (n). Significant difference versus control *P < 0.05 and †P < 0.01 with unpaired t test.